Abstract Background Somatic copy number alternation (SCNA) is a common feature of the cancer genome and is associated with cancer etiology and prognosis.The allele-specific SCNA analysis of a tumor sample aims to identify the allele-specific copy numbers of both alleles, adjusting for the ploidy and the tumor purity.Next generation sequencing platf
All animal cells use the motor cytoplasmic dynein 1 (dynein) to transport diverse cargo toward microtubule minus ends and to organize and position microtubule arrays such as the mitotic spindle.Cargo-specific adaptors engage with dynein to recruit and activate the motor, but the molecular mechanisms remain incompletely understood.Here, we use struc
SKIN FOOD Indigenously made rocking cradle is frequently used in rural India.We report strangulation from an indigenously made rocking cradle in an 11-month-old female child.The unique mode of injury and its mechanism have been discussed.Strangulation is an important cause of homicidal and suicidal injury in adults but in children it is usually acc
Piston-powered aircrafts rely on 100 low lead (100LL) Aviation Gasoline (AVGAS) for safe operation.AVGAS has high levels of Tetraethyl Lead (TEL).TEL is an additive which is added Tub Bearing in aviation fuels to assist in anti-knocking.The main reason for continuation of TEL as an additive in AVGAS is because aircraft engines are prone to engines
ABSTRACT Objective: To describe a unique situation of a sewing needle lodged in the parapharyngeal space and elucidate the problems encountered in its successful removal.Methods: Design: Case Report Setting: Tertiary Private Hospital Patient: One Result: A 24-year-old male tailor accidentally swallowed a sewing needle that pierced the oropharyngeal